Search on: ANTIDEPRESSIVE AGENTS 
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Descriptor English:   Antidepressive Agents 
Descriptor Spanish:   Agentes Antidepresivos 
Descriptor Portuguese:   Antidepressivos 
Synonyms English:   Thymoanaleptics
Thymoleptics
Antidepressants  
Tree Number:   D27.505.954.427.700.122
Definition English:   Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. 
Indexing Annotation English:   GEN or unspecified; prefer specific groups or specific antidepressive agents; consider also DEPRESSION /drug ther
See Related English:   Monoamine Oxidase Inhibitors
 
History Note English:   66; PSYCHIC ENERGIZERS was see ANTIDEPRESSIVE AGENTS 1963-94; THYMOLEPTICS was see TRANQUILIZING AGENTS 1969-78 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications diagnostic use
economics history
immunology isolation & purification
metabolism pharmacology
pharmacokinetics poisoning
radiation effects supply & distribution
standards toxicity
therapeutic use urine
Record Number:   935 
Unique Identifier:   D000928 

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